Interessant3 #147 | 🧬Life Extension, 🇪🇸 Spanish Wage Stagnation, 🛠 Indie-Hacker Playbook
Three Interesting Things for W/C 2025-06-29
1.
: “Biotech must be accelerated to lengthen human life”🏥 Twentieth-century gains came from scrubbing out “extrinsic” killers such as sanitation, vaccines and safer roads, but that well is now dry.
📉 Each extra year of life today needs about 2.5× the all-cause-mortality cut that was required in 1900, so old tactics deliver ever-smaller returns.
🧬 Caloric-restriction hype works for short-lived, metabolically fragile species yet does nothing for long-lived models, so extension is not the same as normalisation.
❤️ Heart-disease care highlights the bind: fewer die of acute infarctions, more survive to chronic failure, and existing drugs only nudge the curve.
🚀 Conclusion: only rapid biotech innovation such as gene editing, senolytics and organoid repair can push the survival curve rightwards, with patents and slow trials acting as choke-points.
🔗 Eliminating distractions in longevity
2. Spanish Wage Stagnation
Spain is going through a political crisis at the moment, however a perhaps even more worrying trend is that its wages have essentially stagnated in the past 30 years.
📊 Eurostat data expose stark divergence in employee wages: Ireland rockets (+64 % to +72 %) while Italy (-2 % to +3 %) and Spain (+3 % to +6 %) stall.
🔧 Structural culprits include low productivity growth, rigid sectoral bargaining and slow judicial processes in the laggards.
🧩 Northern Europe such as Denmark and Sweden shows steady, broad-based wage growth without boom-bust drama.
3. Pierre de Wulf, “10 Time- and Money-Saving Tips for Indie-Hackers”
Pierre de Wulf is the founder of ScrapingBee, which he bootstrapped to 5 million USD ARR and exited for eight figures. He shares a playbook to help others on the same journey save time and money. A few highlights below.
💡 Need an idea? Scan Capterra or G2 one-star reviews and build the fix.
🧪 One-minute MVP: drop a fake UI screenshot into niche LinkedIn groups and measure interest.
⚙️ Netlify 15-second deploy plus AWS credit bundles cut infrastructure costs to near zero.
🗣️ Offer 10× what your free plan offers for a 15-minute call to collect feedback.
🔗 Thread, Practical tips for the Indie-Hacker journey
Join us next week for three more intriguing topics that challenge the norm and expand your horizons! ✌️
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